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All Journal Majalah Kedokteran Gigi Indonesia Dental Journal (Majalah Kedokteran Gigi)
Ayub, Aulia
Dentist Study Program, Faculty Of Dentistry, Universitas Gadjah Mada, Yogyakarta
Dentistry

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Effect of jackfruit seed fortification on high calcium milk on bone collagen density Aulia Ayub; Fun Nagede Adinsyah; Arum Trisnaningtyas Sugiyanto Putri; Presty Dwi Fitriani; Risma Martasuri; Tetiana Haniastuti
Majalah Kedokteran Gigi Indonesia Vol 4, No 2 (2018): August
Publisher : Faculty of Dentistry, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (283.076 KB) | DOI: 10.22146/majkedgiind.25979

Abstract

Osteoporosis is a bone disease characterized by reduced bone mass and damage to the microarchitecture of bone tissue. One of osteoporosis types is primary type-1 osteoporosis or postmenopausal osteoporosis due to estrogen deficiency. Calcium is an important mineral that plays a central role in the formation of bone strength structure. Jackfruit seeds (Artocarpus heterophyllus) contain isoflavones that can replace the role of estrogen in the body. Fortification of jackfruit seeds and high calcium milk can be a potential alternative for the treatment of postmenopausal osteoporosis. The purpose of this study was to determine the effect of drinking high calcium milk fortified with jackfruit seed extract (Artocarpus heterophyllus) on alveolar bone collagen fiber density of menopause induced rats. Twenty-five Sprague dawley rats were included in this study. Twenty Sprague dawley rats were ovariectomized, while 5 rats were left untreated (normal control group). Seven days after ovariectomy was performed, 5 rats were treated with fortification of jackfruit seed extract and high calcium milk, 5 rats were treated with jackfruit seed extract, 5 rats were treated with high calcium milk, and 5 rats were left untreated (ovariectomized control group). The treatments were done for 28 days. The rats were euthanized and the alveolar bone was taken and processed for a histological specimen. Alveolar bone collagen fibers were observed under a binocular microscope with 100 magnification. Kruskal-Wallis result showed there was a significant difference in the alveolar bone collagen fiber density among these groups (p<0.05). Mann-Whitney U Test showed a significant difference (p<0.05) in the alveolar bone collagen fiber density of the rats treated with fortification of jackfruit seed extract and high calcium milk compared to the group treated with jackfruit seed extract, that with high calcium milk, or ovariectomized control group. No significant difference in alveolar bone collagen fiber density was found between the group treated with fortification of jackfruit seed extract and high calcium milk and the normal control group (p>0.05). In conclusion, consuming high calcium milk fortified with jackfruit seed extract increases the density of alveolar bone collagen fibers.
Interdisciplinary management of Class III malocclusion with cleft lip and palate Retno Iswati; Cendrawasih Andusyana Farmasyanti; Aulia Ayub; Anne Marie Kuijpers-Jagtman; Ananto Ali Alhasyimi
Dental Journal Vol. 56 No. 1 (2023): March 2023
Publisher : Faculty of Dental Medicine, Universitas Airlangga https://fkg.unair.ac.id/en

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/j.djmkg.v56.i1.p7-12

Abstract

Background: A cleft lip and palate (CLP) is one of the most common birth defects of the face. Individuals with CLP often have a significant growth disturbance of the maxilla along three dimensions, resulting in skeletal Class III malocclusion and cross bite. Oral rehabilitation can be complicated. Purpose: The purpose of this case study was to highlight the necessity of sequential interdisciplinary management to improve facial esthetics and correct functional disturbances for a patient with CLP. Case: The patient was a 20-year-old woman complaining of the unpleasant appearance of her upper front teeth. She had a concave profile with Class III skeletal patterns (SNA: 78O; SNB: 82O; ANB: -4O), cleft lip and palate, and an anterior and posterior crossbite. Case Management: A combined orthodontic, endodontic, conservative, periodontic, and prosthetic approach was proposed to achieve normal occlusion, function, and a harmonious profile. The combination of rapid maxillary expansion and fixed orthodontics (standard edgewise appliance) established good general alignment and a Class I relationship. After 15 months of treatment, both the posterior and anterior crossbite had been completely corrected. In order to address the gingival margin differences, the patient was instructed to make another appointment with the periodontist and was referred to the restorative dentist for veneer restorations and the prosthodontist for fabrication of a removable retainer with obturator. Conclusion: This interdisciplinary approach greatly improved both esthetics and function. The patient was satisfied with the results achieved.
Co-Authors Ananto Ali Alhasyimi Anne Marie Kuijpers-Jagtman Arum Trisnaningtyas Sugiyanto Putri Cendrawasih Andusyana Farmasyanti Fun Nagede Adinsyah Presty Dwi Fitriani Retno Iswati Risma Martasuri