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All Journal Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran
Berlie Kleinfelter Neonufa
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Health Professions Public Health

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Laporan Kasus: Manajemen Anemia Hemolitik Autoimun (AIHA) pada Wanita Berusia 38 Tahun Berlie Kleinfelter Neonufa; Martino Handoyo
Vitalitas Medis : Jurnal Kesehatan dan Kedokteran Vol. 3 No. 2 (2026): April: Vitalitas Medis : Jurnal Kesehatan dan Kedokteran
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/vimed.v3i2.2964

Abstract

Background: Autoimmune Hemolytic Anemia (AIHA) is a rare immunological condition that causes the destruction of red blood cells through autoantibodies. Case Presentation: This report discusses the case of a 38-year-old woman who presented with complaints of weakness and acute dizziness at RedaBolo, with a history of recurrent anemia over the past six months. Physical examination revealed clear signs of hemolysis, including icteric sclera and splenomegaly. Laboratory findings confirmed severe anemia (Hb 5.0 g/dL) with varied peripheral blood cell morphology (spherocytes, schistocytes, and teardrop cells). The diagnosis was supported by a positive Coombs test and hyperbilirubinemia.  Management: The therapeutic strategy focused on hemodynamic stabilization through transfusion of 4 units of packed red blood cells (PRC), immunosuppression with methylprednisolone 125 mg/day, and gastric protection. Conclusion: These interventions yielded satisfactory results, with the patient achieving significant clinical improvement and a hemoglobin level of 9.5 g/dL by the fourth day of treatment.
Co-Authors Martino Handoyo