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All Journal Majalah Patologi Indonesia CRJIM (Clinical and Research Journal in Internal Medicine)
Patikawa, Febria Rizky
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PROFIL HISTOPATOLOGIS LIMFOMA EKSTANODAL: PENELITIAN RETROSPEKSTIF SELAMA 5 TAHUN Patikawa, Febria Rizky; Kurniasari, Nila; Fauziah, Dyah
Majalah Patologi Indonesia Vol. 35 No. 1 (2026): MPI
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v35i1.659

Abstract

Introduction Extranodal lymphomas account for 30% of all lymphomas. The diverse location and various clinical manifestation of extranodal lymphoma lead to difficulty in diagnosis. The different types of extranodal lymphoma behave and respond differently to therapy. The information regarding the incidence of extranodal lymphoma is still limited, hence further study is needed. Methods Descriptive observational research design with a retrospective approach. This study used data from anatomical pathology examinations at the Dr. Soetomo General Academic Hospital, Surabaya, over a 5-year period, with the diagnosis of lymphoma originating from organs other than lymph nodes and no prior history of lymphoma in the lymph node. Result As many as 379 cases were diagnosed as lymphoma originating from extranodal. The highest age group was 51-60 years old (27.70%), male patient is slightly higher (55.91%) and the highest location is in the head and neck region (48.11%). On anatomical pathology examination, the most common diagnosis were high grade B cell NHL (48.11%). Conclusion This study showed the incidence of extranodal lymphoma, with the majority of cases occurring in the fifth decade of life, with M:F ratio is 1.33:1 and the most common location was in the head and neck area. The most common histological diagnosis was high grade B cell NHL, with DLBCL being the most common subtype. This study provided initial information on the epidemiology of extranodal lymphoma at Dr. Soetomo General Academic Hospital in Surabaya. Further research is needed to determine the relationship between variables and patient survival. 
Diagnostic Delay in advanced Gastroesophageal Adenocarcinoma presenting as Chronic Neurogenic Dysphagia: Gastroesophageal Adenocarcinoma and Chronic Neurogenic Dysphagia Abshori, Nuril Farid; Kakiay, Ferdinandus Stevanus; Ahdi, Iwal Reza; Patikawa, Febria Rizky
Clinical and Research Journal in Internal Medicine Vol. 7 No. 1: Volume 7 No 1, May 2026
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2026.007.01.15

Abstract

Advanced adenocarcinoma of the esophagogastric junction (AEGJ) may mimic benign or neurogenic swallowing disorders, leading to delayed diagnosis. We report a 65-year-old man with a two-year history of progressive dysphagia initially attributed to neurogenic causes following an ischemic stroke. The patient developed recurrent vomiting, epigastric pain, and significant weight loss (16 kg). On admission, he appeared cachectic (BMI 16.7 kg/m²) with anemia (Hb 7.7 g/dL) and hypoalbuminemia (2.4 g/dL). Contrast-enhanced CT revealed an infiltrative mass involving the distal esophagus and gastric fundus with lymphadenopathy, while endoscopy showed a friable obstructive lesion confirmed as adenocarcinoma on biopsy. A feeding jejunostomy was performed for nutritional optimization prior to oncologic therapy. The diagnostic delay resulted from anchoring bias, in which dysphagia was misinterpreted as neurogenic rather than structural. This case emphasizes the importance of early endoscopic evaluation in elderly patients with chronic progressive dysphagia, weight loss, or anemia, and highlights the need for clinician awareness of cognitive biases to prevent late-stage presentation and improve clinical outcomes.
Co-Authors Abshori, Nuril Farid Ahdi, Iwal Reza DYAH FAUZIAH, DYAH Kakiay, Ferdinandus Stevanus Nila Kurniasari