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Dzikri, Dykall Naf’an
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Health Professions

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Analisis Determinan Sosiodemografi dan Perilaku Terkait Kejadian Servisitis dalam Kehamilan: Tinjauan Sistematik Kencana, Nabila Safhira Titan; Prakoeswa, Flora Ramona Sigit; Pramuningtyas, Ratih; Soekiswati, Siti; Dzikri, Dykall Naf’an
Cermin Dunia Kedokteran Vol 53 No 04 (2026): April 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i04.1901

Abstract

Introduction: Cervicitis is an inflammation of the cervix that can lead to serious complications during pregnancy. The objective of this article is to identify risk factors associated with the incidence of cervicitis in pregnant women. Methods: Literature review with narrative analysis. Article searches were conducted on the ScienceDirect, Sage, Google Scholar, and Garuda databases using predetermined keywords. A total of 2,009 articles were obtained from the 4 databases. After the screening process based on the inclusion and exclusion criteria, 15 articles were obtained for analysis. Results: Analysis of 15 articles showed that the incidence of cervicitis in pregnant women is influenced by several risk factors, including: (1) Demographic characteristics such as age and ethnicity; (2) Behavior and lifestyle including sexual intercourse and smoking patterns; (3) Obstetric and gynecological health history; (4) Socio-economic factors; (5) Living environment; and (6) Personal hygiene. The most consistently reported factors were poor personal hygiene, low socioeconomic status, and risky sexual behavior. Conclusion: Cervicitis in pregnant women is associated with complex and multidimensional risk factors. Identification of these factors is important for developing prevention and early detection strategies, thereby reducing the incidence of cervicitis and preventing serious pregnancy complications.
Perbedaan Skala Analog Visual Nyeri dan Kadar Protein C-reaktif Sensitivitas Tinggi Setelah Pemberian Fentanil dan Ketamin Perioperatif pada Pasien Pasca-laparotomi: Sebuah Uji Klinis Terkontrol Acak Buta Ganda: Penelitian Mahendra, Adiptya Cahya; Thamrin, Muhammad Husni; Putro, Bambang Novianto; Dzikri, Dykall Naf’an
Cermin Dunia Kedokteran Vol 53 No 08 (2026): Agustus 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i08.1783

Abstract

Introduction: Postoperative pain remains a significant challenge in perioperative management. This study aims to analyze the differences in pain scores using the visual analog scale (VAS) and high-sensitivity C-reactive protein (hsCRP) levels between perioperative ketamine administration and perioperative fentanyl administration in post-laparotomy patients. Methods: A double-blind randomized controlled trial was conducted on 24 laparotomy patients divided into ketamine (n = 12) and fentanyl (n = 12) groups. The ketamine group received a 0.2 mg/kg bolus followed by a 0.1 mg/kg/hour infusion, while the fentanyl group received a 0.5 mcg/kg/hour infusion during surgery; drug administration was stopped immediately after extubation. VAS scores were assessed at 4 and 8 hours postoperatively, and hsCRP levels were measured preoperatively and 6 hours postoperatively. Statistical analysis used independent t-tests, Mann-Whitney U tests, and Pearson correlation. Results: The ketamine group showed significantly lower VAS scores at 4 hours postoperatively (2.92 vs 5.25; p = 0.017), but no significant difference at 8 hours (6.00 vs 5.75; p = 0.514). Postoperative hsCRP levels were lower in the ketamine group compared to fentanyl (4.58 vs 7.77; p = 0.006). A positive correlation was found between increased VAS scores and elevated hsCRP (r = 0.566; p = 0.004). Conclusion: Ketamine provides significantly superior early postoperative analgesia and more effectively suppresses the acute inflammatory response than fentanyl. However, its analgesic advantage diminishes by 8 hours, indicating the need for a multimodal strategy for sustained postoperative pain management.
Co-Authors Flora Ramona Sigit Prakoeswa Kencana, Nabila Safhira Titan Mahendra, Adiptya Cahya Muhammad Husni Thamrin, Muhammad Husni Putro, Bambang Novianto Ratih Pramuningtyas Siti Soekiswati