Article Per Year (5 Year)
p-Index From 2021 - 2026
0.23
P-Index
This Author published in this journals
All Journal Indonesian Journal of Multidisciplinary on Social and Technology
Darban, Adabi
Unknown Affiliation
Computer Science & IT Economics, Econometrics & Finance Engineering Social Sciences

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
A Integration of Next-Generation Sequencing in Health Biotechnology: A Systematic Synthesis and Meta-Analysis of Diagnostic, Clinical, and Economic Impacts. Darban, Adabi; Maulana, Akram caesar; Rachmawati, Rachmawati
Indonesian Journal of Multidisciplinary on Social and Technology Vol. 4 No. 2 (2026): Maret - Juni
Publisher : PT Ilmu Data Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69693/ijmst.v4i2.8037

Abstract

Technological development Next-Generation Sequencing(NGS) has revolutionized the fields of molecular diagnostics and healthcare biotechnology through comprehensive, high-throughput, and precision genomic approaches. This study aims to systematically synthesize scientific evidence on the diagnostic, clinical, and economic impact of NGS implementation in modern healthcare. The methods used areSystematic Literature Review(SLR) with reference to the PRISMA guidelines, using the Scopus database for the 2020–2026 publication period. Of the 3,491 identified articles, 20 met the inclusion criteria and were analyzed qualitatively. The synthesis results showed that NGS significantly improves diagnostic sensitivity and accuracy, accelerates diagnosis, and supports the application of precision medicine, particularly in genetic diseases, cancer, and infections. Furthermore, the implementation of NGS has been shown to provide clinical benefits in the form of improved patient outcomes and therapy efficiency, and demonstrates potentialcost-effectivenesslong-term. However, challenges related to regulation, ethics, genomic data privacy, and access disparities remain major concerns. Overall, NGS is a crucial pillar in the sustainable transformation of genomics-based health systems.
Co-Authors Maulana, Akram Caesar Rachmawati Rachmawati