PERAN MAMMALIAN TARGET OF RAPAMYCIN DALAM EPILEPSI

Machlusil Husna,* Shahdevi Nandar Kurniawan*

Majalah Kedokteran Neurosains
Vol. 34 No. 4 September 2017

TARGET OF RAPAMYCIN MTOR IS A LARGE SERINETHREONINE KINASE WHICH PLAYS MAJOR ROLE IN MANY CELLULAR PROCESSES SUCH AS GROWTH REGULATION AND CELLULAR METABOLISM DEVELOPMENT AND PROLIFERATION OF ADAPTIVE IMMUNE FUNCTION AND CELL DEATH THROUGH APOPTOSIS AND AUTOPHAGY THE MTOR SIGNAL PATHWAY WORKS AS MOLECULAR SYSTEM INTEGRATOR TO SUPPORT CELLULAR AND ORGANISM INTERACTIONS WITH THE ENVIRONMENT