Journal of Engineering and Scientific Research (JESR)
Vol 1, No 1: (June, 2019)

The Improvement of Paclitaxel Cytotoxicity using Nanocellulose based Nature Resources

Nahrowi, R (Unknown)
Setiawan, A (Unknown)
Noviany, Noviany (Unknown)
Sukmana, I (Unknown)
Yuwono, S D (Unknown)

Article Info

Publish Date
15 Jun 2019

Abstract

Paclitaxel is one of the cancer drugs that often used. These drug kills cancer cells byinhibiting mitotic cycle. The efficiency of paclitaxel is increased by the use ofnanomaterials as a carrier of paclitaxel. Nanomaterials can enhance encapsulationefficiency, improve the drug release to the target cell following nanomaterialdegradation, and improve local accumulation of drug in the cell through endocytosisreceptor. Nanomaterial that often used forencapsulation of paclitaxel is a polymerderived from natural resources such as cellulose. The advantages of cellulose as acarrier of paclitaxel are nontoxic, biodegradable, and very abundant from varioussources. One of the potential sources of cellulose for drug delivery system is cassavabaggase.Keywords: Paclitaxel, encapsulation, cell viability, nanocellulose

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Journal Info
Journal of Engineering and Scientific Research (JESR)
Website

Abbrev

ojs

Publisher

Universitas Lampung

Subject

Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Engineering Industrial & Manufacturing Engineering

Description

The focus and scopes of JESR is on but not limited to Mechanical Engineering and Material Sciences, Chemical and Environmental, Industrial and Manufacturing Engineering, Computer and Information Technology, Electrical and Telecommunication, Civil and Geodetic Engineering, Architecture and Urban ...