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All Journal Journal of Engineering and Scientific Research (JESR) JURNAL REKAYASA KIMIA & LINGKUNGAN
S D Yuwono
Department of Chemistry, University of Lampung, Jalan Prof.Dr. Sumantri Brojonegoro 1 Bandar Lampung
Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Control & Systems Engineering Energy Engineering Industrial & Manufacturing Engineering

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The Improvement of Paclitaxel Cytotoxicity using Nanocellulose based Nature Resources Nahrowi, R; Setiawan, A; Noviany, Noviany; Sukmana, I; Yuwono, S D
Journal of Engineering and Scientific Research Vol 1, No 1: (June, 2019)
Publisher : University of Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jesr.v1i1.3

Abstract

Paclitaxel is one of the cancer drugs that often used. These drug kills cancer cells byinhibiting mitotic cycle. The efficiency of paclitaxel is increased by the use ofnanomaterials as a carrier of paclitaxel. Nanomaterials can enhance encapsulationefficiency, improve the drug release to the target cell following nanomaterialdegradation, and improve local accumulation of drug in the cell through endocytosisreceptor. Nanomaterial that often used forencapsulation of paclitaxel is a polymerderived from natural resources such as cellulose. The advantages of cellulose as acarrier of paclitaxel are nontoxic, biodegradable, and very abundant from varioussources. One of the potential sources of cellulose for drug delivery system is cassavabaggase.Keywords: Paclitaxel, encapsulation, cell viability, nanocellulose
Batch and Continuous Lactic Acid Production from Cassava by Streptococcus bovis Razi, Fachrul; Yuwono, S D
Jurnal Rekayasa Kimia & Lingkungan Vol 5, No 1 (2006): Jurnal Rekayasa Kimia & Lingkungan
Publisher : Chemical Engineering Department, Syiah Kuala University, Banda Aceh, Indonesia

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Abstract

Process variables were optimized for the production of lactic acid from cassava by Streptococcus bovis for batch and continuous fermentations. In the batch fermentation, maximum yield 82.5% and maximum lactic acid productivity 2.43 was achieved at 39 oC, pH 5.5 with 50 g/l cassava concentration. In the continuous fermentation maximum productivity lactic acid 1.25 g/l.h was obtained at dilution rate 0.05 /h.
Co-Authors Fachrul Razi Nahrowi, R Noviany Noviany Setiawan, A Sukmana, I