Molekul: Jurnal Ilmiah Kimia
Vol 1, No 1 (2006)

SINTESIS DAN UJI AKTIVITAS ANALGETIKA-ANTIINFLAMASI SENYAWA N-(4t-butilbenzoil)-p-aminofenol

Sri Sutji Susilowati (Jurusan Kimia, Program Sarjana MIPA Unsoed Purwokerto)
Santi Nur Handayani (Jurusan Kimia, Program Sarjana MIPA Unsoed Purwokerto)

Article Info

Publish Date
01 Nov 2006

Abstract

The synthesis of N-4t-butyl benzoil-p-aminophenol has been done by reacting p-aminophenol and N-4t-butyl benzoil chloride compounds, then the products were isolated and analyzed by TLC, melting point determination, UV/Vis Spectrofotometry, infra red spectrofotometry and mass spectrometry. The synthesis yield of N-4t-butylbenzoil-p-aminophenol was 33,52%, with the compound melting point between 192-194 oCThe determination of analgesic (ED50 of % analgesic activity ) and anti inflammatory activity (ED50 of edema inhibition) gave the ED50 of % analgesic activity was 144 mg/kg and ED50 of % edema inhibition was 43,24 mg/kg.

Copyrights © 2006




Citation Download
RIS
EndNote, Reference Manager, ProCite
BibTex
Latex, Jabref
Full PDF
271.277 KB
Original Source
Download Original
Google Scholar
Check in Google Scholar
Journal Info
Molekul: Jurnal Ilmiah Kimia
Website

Abbrev

jm

Publisher

Universitas Jenderal Soedirman

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

MOLEKUL is a peer-reviewed journal of chemistry published by the Department of Chemistry, Faculty of Mathematics and Natural Sciences, Jenderal Soedirman University, Indonesia. Publishing frequency 2 issues per year, on May and November. This Journal encompasses all branches of chemistry and its ...