JFIOnline
Vol 6, No 3 (2013)

Aktivitas Antioksidan dan Penghambat Xantin Oksidase dari Ekstrak Buah Andaliman (Zanthoxylum acanthopodium DC.)

Kristanty, Ruth Elenora (Unknown)
Mun'im, Abdul (Unknown)
Katrin, . (Unknown)



Article Info

Publish Date
18 Apr 2014

Abstract

The fruits of andaliman (Zanthoxylum acanthopodium DC.) are well known in North Sumatera and commonly used as seasoning for Batak traditional cuisine. Aims of this study were to determine the scavenging activity of free radicals and xanthine oxidase inhibitory activity from the andaliman fruit extracts after macerated garually in petroleum ether, dichloromethane, ethyl acetate, n-butanol, and methanol. Activity assay were evaluated in vitro by using DPPH and enzyme xanthine oxidase. The result showed that n-butanol extract has medium antioxidant activity with IC50 values of 53.51 μg/mL and methanol extract has strong antioxidant activity with IC50 values of 26.39 mg/mL. Xanthine oxidase inhibitory activity of the extract given by n-butanol and methanol are very strong with IC50 values of 3.69 μg/mL and 4.03 μg/mL. Keywords : antioxidant, free radical, xanthine oxidase, Zanthoxylum acanthopodium DC.  

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Journal Info

Abbrev

jurnal

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Jurnal Farmasi Indonesia yang diterbitkan oleh Pengurus Pusat Ikatan Apoteker Indonesia. Isi website memuat seluruh jurnal yang telah diterbitkan mencakup semua aspek dalam ilmu pengetahuan dan teknologi kefarmasian antara lain farmakologi, farmakognosi, fitokimia,farmasetika, kimia farmasi, biologi ...