Efektivitas Ekstrak Ethanol, Partisi N-Heksana dan Fraksi Kromatografi Momordica charantia Dalam Menurunkan Glukosa Darah

Ni Luh Putu Kusuma Clara Dewinda
I Nyoman Suartha
Luh Made Sudimartini

Buletin Veteriner Udayana
Vol. 9 No. 2 Agustus 2017

This study aims to determine the effectiveness of the ethanol extract, partition n-hexane, and chromatography fractions Momordica charantia L. in lowering blood glucose levels in experimental diabetic male rats. This study used 25 male rats were divided into five treatment groups P0 (negative control), P1 (positive control), P2 (ethanol extract), P3 (partition n-hexane), and P4 (chromatographic fraction) the variable observed glucose levels blood for 21 days. Blood glucose levels were analyzed on days -1, 0, 4, 11, 18. The bill, which is used in the form of a completely randomized design (CRD). The data obtained and analyzed by using Split in Time. The results showed of giving chromatographic fractions bitter melon 50 mg / kg body weight can reduce blood glucose levels in hyperglycemic rats better than the ethanol extract 200 mg / kg body weight and partition n-hexane 50 mg / kg body weight.