Jurnal Ilmu Kedokteran (Journal of Medical Science)
Vol 11, No 2 (2017): Jurnal Ilmu Kedokteran

Mekanisme Kerja dan Target Molekuler Interleukin-1 receptor antagonist (Anakinra) pada Aterosklerosis

M. Yulis Hamidy (Unknown)

Article Info

Publish Date
22 Nov 2018

Abstract

Inflammation plays an important role in the development and progression of a variety of cardiovascular conditions,most notably coronary atherosclerosis and congestive heart failure. A number of inflammatory molecules have beenimplicated in these processes, including interleukin-1 (IL-1). IL-1 receptor antagonist is an endogenous inhibitor of IL-1, which competitively binds to the IL-1 type I receptor without activating it. Anakinra is a nonglycosylated, recombinantform of human IL-1ra that, like endogenous IL-1ra, competitively inhibits IL-1 by binding the IL-1 type I receptor.

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Journal Info
Jurnal Ilmu Kedokteran (Journal of Medical Science)
Website

Abbrev

jik

Publisher

Universitas Riau

Subject

Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Public Health

Description

Journal of Medical Science receives a script from health and medical lecturer, undergraduate, residents, hospital staff and those who interested in writing scientific papers. The scientific articles posted on JIK include: literature reviews, research article, case report and EBCR (Evidence Based ...