Farmaka
Vol 16, No 3 (2018): Suplemen (September)

REVIEW : STUDI IN-VIVO SEDIAAN TRANSDERMAL KETOPROFEN SEBAGAI ANTIINFLAMASI

QONITA ZAHRA FADHILA (260110150096)
TIANA MILANDA (Unknown)



Article Info

Publish Date
10 Nov 2018

Abstract

ABSTRAK Ketoprofen merupakan obat analgesik yang bekerja sebagai antiinflamasi. Bentuk sediaan transdermal ketoprofen lebih efektif dan lebih nyaman digunakan dibandingkan bentuk sediaan lainnya, karena mampu menghantarkan obat ke dalam sistem aliran darah dengan lebih baik juga efek samping yang ditimbulkan lebih ringan. Pengujian sediaan transdermal ketoprofen secara in-vivo telah dilakukan untuk mengetahui distribusi ketoprofen secara intravena dalam beberapa hewan uji, yang dianalisis menggunakan kromatografi cair kinerja tinggi (KCKT).  Kata kunci: ketoprofen, transdermal, in-vivo, KCKT. ABSTRACT Ketoprofen is an analgesic drug that works as anti-inflammatory. The ketoprofen transdermal dosage form is more effective and more convenient to use than other dosage forms, as it can deliver the drug into the bloodstream system better and the side effects are milder. In-vivo transdermal ketoprofen dosage form analysis has been performed to determine the distribution of ketoprofen intravenously in some test animals, which were analyzed using high performance liquid chromatography (HPLC).  Keywords : ketoprofen, transdermal, in-vivo, HPLC

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Journal Info

Abbrev

farmaka

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Description

Farmaka is replacement for Pharmaceutical Bulletin, published since 1991, with a frequency of four times a year. Editors accept scholarly works of research results and literature review which was closely related to the science, pharmaceutical technology and ...