Farmaka
Vol 14, No 1 (2016): Supplement

Biomarker Penyakit Sindrom Nefrotik Resisten Steroid : Review

QISTY AHLA DZIKRY AL HASIMY (260110130103)
Insan Sunan Kurniawansyah (Unknown)

Article Info

Publish Date
10 Feb 2017

Abstract

Sindrom nefrotik idiopatik merupakan penyakit glomerulus dan umumnya terjadi pada anak, Penyakit ini ditandai dengan proteinuria, hipoalbuminemia, hiperlipidemia dan edema. Steroid resistance nephrotic syndrome (SRNS)  sangat sulit dibedakan dengan sensitive steroid nephrotic syndrom (SSNS). Dibutuhkan biomarker khusus seperti urinary vitamin D-binding protein (uVDBP), soluble urokinase-type plasminogen activator receptor (sUPAR), urinary N-acetyl-beta-D glucosaminidase (uNAG), dan fractional excretion of magnesium (FE Mg). Dari keempat penelitian masing-masing biomarker dapat ditarik kesimpulan bahwa keempat biomarker belum bisa dijadikan sebagai standar biomarker untuk SRNS dikarenakan belum tervalidasinya biomarker, walaupun memiliki hasil yang signifikan.

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Journal Info
Farmaka
Website

Abbrev

farmaka

Publisher

Universitas Padjadjaran

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

Description

Farmaka is replacement for Pharmaceutical Bulletin, published since 1991, with a frequency of four times a year. Editors accept scholarly works of research results and literature review which was closely related to the science, pharmaceutical technology and ...