Loperamide for acute diarrhoea in infancy (a clinical experience)

Pitono Soeparto (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)
Liek Djupri (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)
Hardjono Soeparto (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)
Haroen Noerasid (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)

Paediatrica Indonesiana
Vol 21 No 5-6 (1981): May - June 1981

A total of 94 infants aged below 3 years with acute maetry diarrhoea underwent treatment with loperamide (Normotil, Pharos Indonesia). They were arbitarily divided into group I (46 patients) receiving loperamide and group II (48 patients) receiving loperamide & antibiotics in addition to oral glucose-electrolyte solution. Stools became normal within 3 days in 69.6% of patients in group I and 86% in group 11, and within 7 days in 87% of patients in group 1 and 95.4% in group Il. In 5 patients, diarrhoea worsened within 24 hours, necessitating the administration of i.v.f.d. There were no side-effects encountered during the treatment of loperamide.