Typhoid Fever in Children

Soelistyowati S. (Department of CHild Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Yati Soenarto (Department of CHild Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Hafni Soesilo (Department of CHild Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Widiarto Widiarto (Department of CHild Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Widiatmodjo Widiatmodjo (Department of CHild Health, Gadjah Mada University Medical School, Yogyakarta, Central Java)
Ismangoen Ismangoen

Paediatrica Indonesiana
Vol 22 No 7-8 (1982): July - August 1982

One hundred ana fifty eight cases of Typhoid fever in children are reported as a result of a one year study.Blood Salmonella typhi culture was found in 52.3%, wheereas Widal titer was positive in 57.9% cases. Fever and aneosinophilia were found in all of the 158 patients (100%), While 76.3% had constipation, 59.5% disturbance of consciousness, 98% leucopenia and 33.3% diarrhoea occurring in children below 5 years.The result of treatment with chloramphenicol 75 mg/ kg Bw/day showed that the body temperature retumed to normal in an average of 4.9 days after the  administration of the drug, whereas hospitalization lasted 14.4 days (average). Three pat}ents (/.9o/o) died because of perforation :and bronchopneumonia and 5 failures were considered as caused by drug relsistancy.During this study the typhoid fever morbidity rarte in the hospital was 8.1% with the case fatality r.ate as high ·as 1.6%. The higr.est outbreak happened at the beginning of the rainy season.