Paediatrica Indonesiana
Vol 39 No 11-12 (1999): November - December 1999

Clinical Features and Liver Biochemical Activity of Hepatitis A

S. Zuraida Zulkarnain (Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta)
Anna Tjandarjani (Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta)
Arwin P. Akib (Department of Child Health, University of Indonesia Medical School/Dr. Cipto Mangunkusumo Hospital, Jakarta)



Article Info

Publish Date
15 Mar 1999

Abstract

A descriptive, cross sectional study, was conducted between January 1st 1993 until June 30th 1998. The objective of the study is to describe clinical features and liver biochemical activity of hepatitis A. Ninety three cases of hepatitis A (55,0%) were colleed from hospitalized acute viral hepatitis. Only 92 cases were evaluated, becuse no initial data was found in one case. The highest number of cases (44.5%) was in the age group of 5-10 years, 53 cases (57.6%) were boys and 39 cases (42.4%) were girls. From the history of illness 82 cases (89: 1 %) with jaundice, 60-80% with fever, nausea, vomiting, and anorexia. Abdominal pain and weakness in 35%, less than 12% wlth headache, myalgia, diarrhea, common cold and cough. Fifty cases (54.3%) were underweight based on weight for age. From physical examination 89.1% of cases showed Jaundice, 68.5% hepatomegaly, 23.9% abdominal tenderness, 18.5% fever, 6.5% splenomegaly, 5% pale, and 1.1% unconscious. Test of biochemical activity showed wide range result, AST 22-2869 IU/L, ALT 22-2880 IU/L, conjugated bilirubin 0.07-20.27 mg/dL and unconjugated bilirubin 0.14-11.89 mg/dL. Prolonged cholestatic, fulminant hepatitis and anerma were found in less than 3.2% of cases.

Copyrights © 1999






Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...