Paediatrica Indonesiana
Vol 39 No 11-12 (1999): November - December 1999

Clinical manifestation of drug allergy in children

Ariyanto Harsono (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)
Anang Endaryanto (Department of Child Health, Airlangga University Medical School/Dr. Soetomo Hospital, Surabaya, East Java)



Article Info

Publish Date
15 Mar 1999

Abstract

In the period of January-December 18 cases of Drug Allergy were recognized, 4 cases from the allergy clinic, 8 cases were referred from outpatient clinic, 6 cases were referred from inpatient ward. The clinical manifestation varied from urticaria 5 cases (30%), Steven Johnson Syndrome 2 cases ( 12%), maculopapular rash 2 cases (12%), Drug fever 2 cases (12%), Fixed drug eruption 1 case (6%), exanthem 1 case (6%), Quinke's edema 5 cases (30%) consisted of 2 cases Quinke's edema only, 2 cases with urticaria, 1 case with drug fever. The underlying disease of these cases were upper respiratory tract infection 5 cases, chronic cough 2 cases, Asthma 5 cases, diarrhea 1 case cerebral abscess 1 case, Dengue Haemorrhagic Fever 1 case and Epilepsi 1 case. The mainstay of treatment was discontinuation of the offending drug. Drug substitution were given to patients nescessitated continuation of drugs, antihistamines were given to patients with urticaria and Quinke's edema. Two cases with Steven Johnson syndrome received supportive treatment and hydrocortisone intravenously.

Copyrights © 1999






Journal Info

Abbrev

paediatrica-indonesiana

Publisher

Subject

Health Professions Medicine & Pharmacology

Description

Paediatrica Indonesiana is a medical journal devoted to the health, in a broad sense, affecting fetuses, infants, children, and adolescents, belonged to the Indonesian Pediatric Society. Its publications are directed to pediatricians and other medical practitioners or researchers at all levels of ...