Farmasains : Jurnal Ilmiah Ilmu Kefarmasian
Vol. 4 No. 2 (2017)

Uji Aktivitas Penangkapan Radikal Bebas Ekstrak Etanol Daun Mangkokan (Nothopanax scutellarium (Burm.f) Merr.) Menggunakan Metode DPPH (1,1-Difenil-2-Pikrilhidrazil) dengan Variasi Suhu Pengeringan

fitri farida (Unknown)
any guntarti (Unknown)



Article Info

Publish Date
31 Oct 2017

Abstract

Mangkokan leaves contains flavonoids that are known as natural antioxidant source. The aim of this study is to find the effect of drying temperature variations towards free radical scavenging activity of mangkokan leaves. Mangkokan leaves macerated with 96% ethanol and dried at 40oC, 50oC, and 60oC. Then were macerated with ethanol 96%. Antioxidant activity tested by DPPH method and quercetin was used as positive control. Dry shrinkage with temperatures at 40oC, 50oC, and 60oC were: (9.25 ± 0.276)%; (8.76 ± 0.348)% and (7.97 ± 0.372)%, respectively. Water content at 40oC, 50oC and 60oC were: (5.13 ± 0.575)%; (4.53 ± 0.512)% and (4.04 ± 0.575)%, respectively. The antioxidant potency of 96% ethanolic mangkokan leaves by ES50 value at drying temperatures 40oC, 50oC, 60oC and quercetin were (1.75 ± 0.058); (2.39 ± 0,089); (5.38 ± 0,078) mg/ml and (9.16x10-4 ± 4.36x10-5) mg/ml. Ethanolic extract of mangkokan leaves which dried at 40oC has biggest radical DPPH scavenging activity but much weaker than quercetin.

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Journal Info

Abbrev

farmasains

Publisher

Subject

Medicine & Pharmacology

Description

Farmasains: Jurnal Ilmiah Ilmu Kefarmasian is an national journal published by Faculty of Pharmacy and Science University of Muhammadiyah Prof. DR. HAMKA. Farmasains: Jurnal Ilmiah Ilmu Kefarmasian is aimed at being a medium for research results dissemination and scientific paper exchanges on the ...