ANTIMICROBIAL ACTIVITY OF Actinomycetes EXTRACT FROM SEA WATER OF RANDAYAN ISLAND, BENGKAYANG AGAINTS Salmonella sp.

., Rahmi dianty

Jurnal Mahasiswa PSPD FK Universitas Tanjungpura
Vol 3, No 1 (2015): Jurnal Pendidikan Dokter Kalbar

Background: Typhoid fever is still problem in the world. Actinomyetes,microbe produces antibiotic. Discovery new antibiotic is a need to handleMultiple Drug Resistant Typhoid Fever. Isolation Actinomycetes whichproduces secondary metabolite can be made by exploring marine.Objective: to know the potentially of Actinomycetes isolate which wasfounded as antibiotic producer againt Salmonella sp. Method:Antimicrobial activity of 16IM7 isolate  extract from Randayan Island,Bengkayang Disctrict is observated  againt Salmonella sp. Dose variationis 5, 10, and 15 µg.  Positive control is cefixime 10 µg/disk and negativecontrol is etil asetat. Result: based on the research by well diffusion agarmethode is known that 16IM7 isolate  extract could inhibit Salmonella spand optimum dose is 10µg. Minimum inhibit consentration (MIC) is  0,25µg /well.Conclusion: Actinomycetes was isolated from marine potentiallyas antibiotic producer against Salmonella sp.Kata Kunci: typhoid fever, antimicrobial, Actinomycetes, Salmonella sp.