PENGARUH PEMBERIAN MADU TERHADAP FUNGSI GINJAL (UREUM DAN KREATININ) TIKUS PUTIH (Rattus norvegicus L.) JANTAN GALUR WISTAR YANG DI INDUKSI TUAK.

ROBITAH ASFUR (Universitas Muhammadiyah Sumatera Utara)
GUNAWAN SADEWO (Departemen Farmakologi Universitas Muhammadiyah Sumatera Utara)

JURNAL ILMIAH KOHESI
Vol 3 No 2 (2019): JURNAL ILMIAH KOHESI

Introduction: Honey is one of the human food ingredient produced by bees. Honey is a food that is special and has a high nutritional value. Honey contains many minerals, flavonoids and phenolic acids substance that serves as an antioxidant agent that can prevent kidney damage. A drink or a traditional medicine belonging to the liquor if it contains alcohol> 1%. Tuak is a typical alcoholic beverage from batak, made from coconut or palm stems taken the water and then mixed with raru. Objective: This research is to know the effectiveness of honey in renal function (urea and creatinine) white rat (Rattus norvegicus L.) Wistar male in induction palm wine. Methodology: The research used True Experiment method with "pretest-posttest with control group design" design Result: The results show that the P value for urea number is <0.05, and the P value for creatinine levels also showing <0.05. Conclusion: there is an effect of honey in renal function (urea and creatinine) white rat (Rattus norvegicus L.) Wistar male in induction palm wine (Tuak ).