Standardization of Phyllanthus niruri and Sonchus arvensis as Components of Scientific Jamu

Nikmatul Ikhrom Eka Jayani (Department of Pharmaceutical Biology, Faculty of Pharmacy University of Surabaya)
Alfian Hendra Krisnawan (Department of Pharmaceutical Biology, Faculty of Pharmacy University of Surabaya)
Nina Dewi Oktaviyanti (Department of Pharmaceutical Biology, Faculty of Pharmacy University of Surabaya)
Kartini Kartini (1) Department of Pharmaceutical Biology, Faculty of Pharmacy University of Surabaya 2) Centre for Information and Development of Traditional Medicine, University of Surabaya)

Majalah Obat Tradisional
Vol 25, No 1 (2020)

Saintifikasi Jamu, or the scientific investigation of Jamu, is an evidence-based process to ensure the safety and efficacy of herbal medicine through health service research. Jamu has been empirically explored as a composition of various crude drugs, hence called as Scientific Jamu. Phyllanthus niruri and Sonchus arvensis are two of the 30 medicinal plants processed into Scientific Jamu. Components of the Scientific Jamu are standardized to ensure that these materials meet the predefined quality. This study was aimed to determine the specific parameters (macroscopic, microscopic, total flavonoid content, water-soluble extract content, and ethanol-soluble extract content) and non-specific parameters (loss on drying, total ash content, and acid insoluble ash content) of Phyllanthus niruri and Sonchus arvensis collected from Batu, Tawangmangu, and Bogor. The methods of the determination referred to the Indonesian Herbal Pharmacopoeia 1st Edition (2008). The results showed that Phyllanthus niruri and Sonchus arvensis from the three places did not meet the standard requirement.