JFL : Jurnal Farmasi Lampung
Vol. 8 No. 2 (2019): JFL: Jurnal Farmasi Lampung

Ethanol Fraction of Corn Silk (Zea mays L.) to Decrease Uric Acid Levels in Male White Mice

Laila Susanti (University of Tulang Bawang Lampung)



Article Info

Publish Date
27 May 2021

Abstract

Corn silk (Zea mayz L.) were empirically used by the community in some regions as traditional remedies for hypertension,kidney stones,diabetes mellitus, urinary tractinfections and gout. This study aimed to determine the effect of corn silk ethanol fraction on decrease uric acid levels in male white mice.corn silk were extracted by macerate used 70% ethanol for 4 days.Urin acid test was performed on male mice induced by beef liver for 7 days.25 mice were grouped into 5 groups, groups dose I, II and III weregiven a fraction at a dose of 27.5 mg / bwBB, 55 mg / bwBB and 110 mg / bwBB, control given Na.CMC 0.5% and as positive controls were given allopurinol dose of 13 mg / bwBB. The five groups were treated orally 1 time a day for 7 days. Decreased uric acid levels were measured and observed on days 7 using an acid (easy touch). The results of ANOVA statistical analysis showed that negative controls gave a significant difference with positive controls, dose I, II and III because the sig value was

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Journal Info

Abbrev

jfl

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology Public Health

Description

The focus of JFL is to become a media for the publication of articles on Pharmaceutical and related practice-oriented subjects in the pharmaceutical sciences, natural medicine and clinic community. The scope of the journal is Pharmaceutical sciences, its research and its ...