Diagnostic Value of Cyclooxygenase-2 Serum Levels in Predicting Preterm Labor

Wiwin Suhandri (Resident of Obstetrics and Gynecology, Faculty of Medicine, Andalas University, Dr. M. Djamil Central General Hospital Padang)
Dovy Djanas (Sub Division of Maternal Fetal Medicine, Obstetrics and Gynecology Department, Faculty of Medicine, Andalas University, Dr. M. Djamil Central General Hospital Padang)

Andalas obstetrics and gynecology journal
Vol 4, No 1 (2020)

Objective: To determine the value of serum cyclooxygenase 2 in predicting preterm laborMethod: Examination of serum COX-2 levels by ELISA method in pregnant women with 28 weeks to 36 weeks of pregnancy compared with pregnant women with ≥37 weeks of gestation at the time of first stage of active phaseResults: It is known that the average COX-2 level in preterm labor is 21.88 ± 18.22 higher than in term labor which is 4.88 ± 2.35 ng / ml, the statistical test results obtained p = <0.001 serum Cyclooxygenase 2 at preterm deliveries and term deliveries. The value of serum cyclooxygenase 2 levels in predicting preterm labor is at a cut point of 7.0.0 ng / ml with a sensitivity of 86.1% and a specificity of 86.1%Conclusion: There were significant differences in serum cyclooxygenase 2 levels in preterm labor and term delivery Keywords: cyclooxygenase 2, memprediksi persalinan preterm, persalinan preterm.