Djanas, Dovy
Sub Division Of Maternal Fetal Medicine, Obstetrics And Gynecology Department, Faculty Of Medicine, Andalas University, Dr. M. Djamil Central General Hospital Padang

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HUBUNGAN LAMANYA PEMBERIAN MAGNESIUM SULFATE PADA PASIEN PEB DAN EKLAMPSIA DENGAN KEJADIAN HIPERMAGNESIUM DI RSUP DR. M. DJAMIL PADANG Mayuliani, Mayuliani; Djanas, Dovy
JOURNAL ANDALAS OBSTETRIC & GYNAECOLOGY Vol 2, No 1 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aogj.2.1.27-31.2018

Abstract

Tujuan?:?Untuk mengetahui hubungan lamanya pemberiaan MgS04 pada pasien PEB dan eklampsia dengan kejadian hipermagnesium.Metode?:?Penelitian ini merupakan observasional komparatif menggunakan desain cross sectional study. Penelitian dilakukan di rekam medis RSUP Dr.M.Djamil Padang selama periode 1 Januari 2016 sampai 31 Agustus 2017 terhadap ibu hamil dengan preeklampsia berat ( PEB) dan eklampsia, didapatkan 30 subyek penelitian yang memenuhi kriteria inklusi. Selanjutnya data dicatat dalam suatu formulir penelitian yang telah disediakan, kemudian dilakukan pengolahan data penelitian. Analisis statistik untuk menilai kemaknaan menggunakan uji chi-squere .Hasil:. Terjadi peningkatan kadar Magnesium pada ibu hamil dengan preeklampsia berat (PEB) dan eklampsia sebanyak 21 koresponden. Peningkatan kadar Magnesium terhadap pasien preeklampsia berat (PEB) dan eklampsia yang mendapatkan tatalaksana MgS04 selama 48 jam sebanyak 16 koresponden ( 84,2%) dan 5 koresponden dengan pemberian MgS04 selama 24 jam.Kesimpulan:?Terdapat hubungan yang bermakna lamanya pemberian Magnesium Sulfat dengan kejadian hipermagnesium pada pasien preeklamsia berat dan eklamsia.Kata kunci?:?PEB, eklampsia, magnesium sulfat, kadar Magnesium
PERBEDAAN RERATA KADAR AKTIVIN A SERUM MATERNAL ANTARA PREEKLAMSIA BERAT DENGAN BUKAN PREEKLAMSIA BERAT Dovy Djanas; Bayu Pramudyo Ariwibowo; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 1, No 1 (2017)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.1.1.30-37.2017

Abstract

At the start of preelampsia there is a failure of cytotrophoblst invasion into the maternal spiral arteries that will lead to decreased uteroplacetal perfusion which will be followed by the failure of the unit fetoplacenter to get enough oxygen from the room intervillous that ultimately lead to a state of hypoxia in placenta. This will cause the expenditure of TNF-α dan IL-1β from placenta and a factors called hypoxia-inducible transcription factors that will spur the trophoblast to produce activin A lot more. This research was conducted by cross sectional method in maternal room of obstetrics and gynecology department of Central General Hospital of Dr. M. Djamil Padang from August 2015 until February 2016 with 20 patients of severe preeclampsia and 20 patients not severe preeclampsia, who met inclusion criteria and there is no exclusion criteria. Then performed statistical analysis using Mann-Whitney test to determine difference in mean maternal activin A serum levels of severe preeclampsia and not severe preeclampsia. The mean maternal serum levels of activin A in severe preeclampsia is 32,55 ± 1,84 ng/ml and in pregnancy with no severe preeclampsia is 8,59 ± 0,59 ng/ ml. Difference in mean maternal serum level of activin A in the two groups was statistically significant (p=0,001). Ma-ternal serum activin A levels is significantly higher in severe preeclampsia than pregnancy with no severe preeclampsia.Keywords: Activin A, severe preeclampsia, not severe preeclampsia
Pengaruh Pemberian Antibiotik Profilaksis Sefazolin, Seftriakson dan Antibiotik Seftriakson Sebelum dan Sesudah Operasi Terhadap Infeksi Luka Pasca Operasi Herti Marni; Dovy Djanas; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.77-86.2020

Abstract

Objective : To determine the effect of giving prophylactic antibiotic ceftriaxone and cefazolin and giving ceftriaxone before and after surgery to the risk of postoperative wound infection in postoperative patients.Method: This study was an experimental study with a post test control group design that looked at the differences in the effect of administration of ceftriaxone, cefazolin, and ceftriaxone before and after surgery on the risk of postoperative wound infection. The population in this study were patients planned for surgery in the Obstetric and Gynelologic Departement of Dr. M. Djamil General Hopital, Padang. The number of samples used by 30 people with a group of 10 people each group. The study began in August until the number of samples was fulfilled. Univariate analysis was used to see the frequency, percentage, mean, and standard deviation. Bivariate analysis using Chi-square test with 95% CI (α <0.05) was used to see differences in the effect of the three antibiotic procedures.Results: There were no cases of postoperative wound infection based on the three procedures used. There was no difference in the effect of prophylactic antibiotics in postoperative infections. Conclusion: There was no difference in the effect of the three procedures for prophylactic antibiotics in postoperative infections.Keywords: Prophylactic Antibiotics, Surgical Wound Infections, Cefazolin, Ceftriaxone, Superficial incisional SSI
PSORIASIS PUSTULARIS DALAM KEHAMILAN Dovy Djanas; Djusar Sulin
Andalas Obstetrics And Gynecology Journal Vol 1, No 2 (2017)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.1.2.86-92.2017

Abstract

Psoriasis is a residual chronic inflammatory skin disease, characterized by a predominance of pustular eruptions accompanied by systemic symptoms such as fever lasting several days. . Psoriasis in pregnancy can lead to spontaneous abortion, stillbirth and preterm birth. Reported the case of Mrs. YS 38 years old, received from the genital skin section of RS M Djamil Padang with a diagnosis of G3P2A0H2 + pustular psoriasis. Fetomaternal ultrasound was performed, obtained biometrics: BPD: 80mm, FL: 61 mm, HL: 54 mm, AC 271 mm, AFI 10.7 cm, SDAU 2.79, estimated fetal weight 1700-1800 grams. Impression: gravid 31-32 weeks, single live fetus intra uterine. Patients are planned for administration of high doses of corticosteroids. Informed consent to the patient and family about the actions to be performed. Corticosteroid was administered as much as 30 mg long term with a dose of prednisone in tappering off every 2 weeks. The patient was discharged for control to the skin clinic and obstetrics, the patient came 12 days later and was consulted to the obstetrics department for termination of the pregnancy but from the obstetrics department there was no confirmation for termination of the pregnancy. The patient then came 13 days later with 18 hours PRM. Pregnancy termination by cesarean section was performed. a baby girl was born with LBW: 3000 gr, PB: 48 cm, A / S: 8/9, there were no congenital abnormalities such as growth disorders, cleft lip, cataracts, and polycystic kidney disease in infants. The cause of psoriasis in this case is probably pregnancy.Keywords: pustularis psoriais, psoriasis, pregnancy, corticosteroid
The Mean Difference of Hemostatic Factors in Severe Preeclampsia and Eclampsia Dyhan Purna Setia; Ferdinal Ferry; Dovy Djanas
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.22-27.2020

Abstract

The aim of this study was to see the difference in the mean ratio of sodium levels between pregnancy with severe preeclampsia and eclampsia. The method in this research is an analytical study using a cross sectional design. The research was conducted in the delivery room Dr. M. Djamil Padang from 15 January 2016 to 31 December 2017. There were 60 patients as research subjects, the sample was divided into 2 groups, namely severe preeclampsia (PEB) and eclampsia. Anamnesis and physical examination were then carried out to obtain data and clinical diagnosis. The data were recorded in a research form that had been provided, then the blood electrolytes were examined for sodium and potassium. Statistical analysis to assess meaning using the T-test. The results showed that in the PEB and Eclampsia groups, it was found that multiparity parity had the highest respondents. This is in accordance with the literature where the incidence of preeclampsia is more often found at gestational age near term. The conclusion of this study there was no significant difference in the mean sodium ratio between preeclampsia, PEB and eclampsia. Keywords: pregnancy condition, PEB, eclampsia, platelet, PT, APTT, and D-Dimer
HUBUNGAN LAMANYA PEMBERIAN MAGNESIUM SULFATE PADA PASIEN PEB DAN EKLAMPSIA DENGAN KEJADIAN HIPERMAGNESIUM DI RSUP DR. M. DJAMIL PADANG Mayuliani Mayuliani; Dovy Djanas
Andalas Obstetrics And Gynecology Journal Vol 2, No 1 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.21-25.2018

Abstract

Objective :To find out the relationship between the duration of MgS04 administration in severe preeclampsia patients and eclampsia with the incidence of hypermagnesium.Method :This study is a comparative observational study using a cross sectional study design. The study was conducted in the medical record of Dr.M.Djamil Padang Hospital during the period January 1, 2016 to August 31, 2017 of pregnant women with severe preeclampsia and eclampsia, found 30 study subjects who met the inclusion criteria. Furthermore, data is recorded in a research form that has been provided, then carried out research data processing. Statistical analysis to assess significance using the chi-square test.Results : Magnesium levels increased in pregnant women with severe preeclampsia and eclampsia by 21 correspondents. Increased Magnesium levels in patients with severe preeclampsia and eclampsia who received MgS04 treatment for 48 hours by 16 correspondents (84.2%) and 5 correspondents with MgS04 administration for 24 hours.Conclusion : There is a significant relationship between the duration of Magnesium Sulfate with the incidence of hyperpermagnesium in patients with severe preeclampsia and eclampsia. Keywords: severe preeclampsia, eclampsia, magnesium sulfate, magnesium levels
PERBEDAAN RERATA FAKTOR HEMOSTASIS PADA PREEKLAMPSIA BERAT DAN EKLAMPSIA Dyhan Purna Setia; Ferdinal Ferry; Dovy Djanas
Andalas Obstetrics And Gynecology Journal Vol 2, No 1 (2018)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.2.1.10-15.2018

Abstract

Objective : To find the difference in mean hemostatic factors in severe preeclampsia and eclampsia.Method : The study was analytic descriptive using a cross sectional study design by looking at the subject's Medical Record according to the time and place of research. The sample is the entire medical record of pregnant women who suffer from preeclampsia and eclampsia in the obstetric and gynecology departments of Dr. M. Djamil Padang Hospital in the period 15 January 2016 to 31 December 2017. The assessment was in the form of assessed platelet levels, PT, APTT and D-Dimer. Samples were taken from populations that met the inclusion criteria and did not have exclusion criteria. Sampling using consecutive sampling techniques taken from the Medical Record Dr. M.Djamil Padang. Statistical analysis to assess significance using the T-Test.Result : The severity the condition of pregnancy the lower the platelet mean and PT. Significant differences were obtained between platelets in PEB and eclampsia (p> 0.05). The mean PT, APTT and D-Dimer showed no significant differences in pregnancy conditions. Statistical test with T-Test did not show significant differences in mean PT, APTT, and D-dimer between eclampsia and PEB (p> 0.05).Conclusion : There were significant differences in mean in platelets, whereas in PT, APTT, and D-dimers in PEB and eclampsia there were no significant differences.Keywords: Pregnancy, severe preeclampsia, eclampsia, platelets, PT, APTT, D-Dimer.
The Effect of Oral Albumin Intake on Serum Albumin Levels in Preeclamsia Patients With Hypoalbuminemia in RSUP Dr. M. Djamil Padang Irwin Fitriansyah; Dovy Djanas; Hafni Bachtiar
Andalas Obstetrics And Gynecology Journal Vol 5, No 1 (2021)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.5.1.69-81.2021

Abstract

Introduction : Albumin main function is maintaining the plasma colloid oncotic pressure. Preeclampsia cause a decrease in serum albumin in the pregnant woman. Low albumin levels increase mortality, longer wound healing and longer hospital stays. The intake of oral albumin is expected to be effective in increasing the level of albumin in the blood.Objective : To determine the effect of freeze dryer method intake compared to liquid snakehead fish extract in patients with preeclampsia and hypoalbuminemia.Material and methods : Using pre and post-test control group design.The total sample was 38 patients with severe preeclampsia with hypoalbuminemia, divided into control and intervention groups. Control was given the intake of liquid snakehead fish extract, in the intervention was given the Freeze dryer method. The research data were analyzed using the Mann Whitney test method and the Wilcoxon test.Results : In the intervention group the mean pretest albumin level was 2.66 ± 0.17 gr / dl and on the 4th day it was 3.13 ± 0.16 gr / dl (p = 0.000). In the control group the mean pretest albumin level was 2.72 ± 0.15 gr / dl and on the 4th day it became 3.06 ± 0.14 gr / dl (p = 0.000). On the 4th day after treatment, the increase in serum albumin levels in the intervention group was 0.47 ± 0.19 gr / dl; whereas in the control group was 0.34 ± 0.10 gr / dl with a value of p = 0.031 (p <0.05).Conclusion : The freeze dryer method (freeze dryer method ) for the Cork Fish Extract resulted in a higher increase in albumin levels than the liquid snakehead fish extract.Keywords: Preeclampsia, Hypoalbuminemia, freeze dryer method of Snakehead Fish Extract
Diagnostic Value of Cyclooxygenase-2 Serum Levels in Predicting Preterm Labor Wiwin Suhandri; Dovy Djanas
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.28-34.2020

Abstract

Objective: To determine the value of serum cyclooxygenase 2 in predicting preterm laborMethod: Examination of serum COX-2 levels by ELISA method in pregnant women with 28 weeks to 36 weeks of pregnancy compared with pregnant women with ≥37 weeks of gestation at the time of first stage of active phaseResults: It is known that the average COX-2 level in preterm labor is 21.88 ± 18.22 higher than in term labor which is 4.88 ± 2.35 ng / ml, the statistical test results obtained p = <0.001 serum Cyclooxygenase 2 at preterm deliveries and term deliveries. The value of serum cyclooxygenase 2 levels in predicting preterm labor is at a cut point of 7.0.0 ng / ml with a sensitivity of 86.1% and a specificity of 86.1%Conclusion: There were significant differences in serum cyclooxygenase 2 levels in preterm labor and term delivery Keywords: cyclooxygenase 2, memprediksi persalinan preterm, persalinan preterm.
Perbedaan Rerata Rasio Kadar Natrium Kalium Maternal Antara Preeklamsia Berat Dan Eklamsia Gunawan Efri Syaputra; Dovy Djanas
Andalas Obstetrics And Gynecology Journal Vol 4, No 1 (2020)
Publisher : Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.4.1.48-52.2020

Abstract

Background: Preeclampsia is a pregnancy-specific syndrome in the form of reduced organ perfusion due to vasospasm and endothelial activation that occurs after 20 weeks of gestational age. eclampsia is the occurrence of seizures in a woman with preeclampsia, Sodium (Na +) and Potassium (K +) play an important role in preeclampsia and eclampsia.Objective: To see the difference in mean sodium potassium ratio between pregnancy with severe preeclampsia and eclampsia.Methods: The study was analytic descriptive using a cross sectional study design by looking at the medical records of the subjects according to the time and place of the study. Samples are all medical records of pregnant women who suffer from pre-eclampsia and eclampsia in the obstetric and gynecology section of  RSUP DR.M.Djamil padang in the period of 15 January 2016 to 31 December 2017, the values of which are sodium, potassium levels and sodium and potassium ratios. Samples were taken from populations that met the inclusion criteria and did not have exclusion criteria. Sampling using a consecuvite sampling technique which was taken from the medical records of RSUP DR. M. Djamil Padang Statistical analysis to assess significance using the T-test.Results: In the Severe preeclampsia and Eclampsia groups it was found that multipara parity had the highest respondents. This is in accordance with the literature where the incidence of preeclampsia is more often found at near term gestational age.Conclusion: There is no significant difference in the average sodium potassium ratio between Severe preeclampsia and EclampsiaKeywords: Severe preeclampsia, eclampsia, sodium and potassium