As-syifaa Jurnal Farmasi
Vol 2, No 2 (2010): AS-SYIFAA Jurnal Farmasi

ISOLASI DAN KARAKTERISASI SENYAWA BIOAKTIF EKSTRAK DIETIL ETER DAUN MIANA (Coleus scutellarioides (L) Benth) YANG AKTIF TERHADAP BEBERAPA MIKROBA UJI

Nurmaya Effendi (Fakultas Farmasi Universitas Muslim Indonesia Makassar)



Article Info

Publish Date
01 Dec 2010

Abstract

Has been conducted research Isolation and characterization of compounds Bioaktif Leaf Extract Diethyl Ether Miana (Coleus scutellarioides (L) Benth) is active against some microbes Test. Maceration extraction is done with diethyl ether. Diethyl ether extracts obtained isolated by method column chromatography with using silica gel as absorbent and hexane-ethyl acetate as dilution fluid, and obtained six fractions. Fraction III-9 was isolated by Preparatif Thin Layer Chromatography (KLTP) and obtained ten tapes.Isolates fraction III-9 identified by chemical reaction with ammonia vapor, aluminum chloride and boric citro, and showed a positive reaction to the flavonoid class of compounds. Data ultraviolet-visible spectroscopy showed a maximum wavelength of 420 nm, while the infrared spectroscopy showed the existence of functional groups - C = C -; - OH; - CH3; and - CH - alifatis and - CH - aromatic. Isolates fraction III-9 with KLT-bioautgraphy was active against  microbial testing Staphylococcus aureus, Candida albicans and Salmonella thyposaKey Words : Leaf Extract Diethyl Ether Miana, Maceration, KLT-Bioautography

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Journal Info

Abbrev

as-syifaa

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology

Description

As-Syifaa Jurnal Farmasi receives manuscripts in Indonesian Language (Bahasa Indonesia) with abstracts in bilingual, both Indonesian and English. We’re open for various fields such as: Pharmacology and Toxicology, Pharmaceutical Microbiology and Biotechnology, Herbal Medicines, Pharmaceutics, ...