The objective of this study was to determine the effect of histology of heart Mus musculus after giving Nano Herbal Rhodomyrtus tomentosa (Haramonting). R.tomentosa (Haramonting) is made on a nanoscale using High Energy Milling (HEM). This research use the Completely Randomized Design (CRD). Treatment consists of 6 groups, namely: Control: CMC 0.5%; T1:100mg/20gBW; T2: 141,42mg/20gBW; T3:200mg/20gBW; T4: 282,82mg/20gBW; T5:400mg/20gBW. The results of histology hearts that there were significant difference (P<0,05) between control group and treatment groups but there was not significantly different in weight of hearts (P>0,05).
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