BIOTROPIA - The Southeast Asian Journal of Tropical Biology
Vol. 24 No. 2 (2017)

ANTIBACTERIAL ACTIVITY OF RED PIGMENT ISOLATED FROM COASTAL ENDOPHYTIC FUNGI AGAINST MULTI-DRUG RESISTANT BACTERIA

Mada Triandala Sibero (Faculty of Fisheries and Marine Science, Diponegoro University, Tembalang, Semarang, Central Java, Indonesia)
Rita Sahara (Department of Aquatic Products Technology, Faculty of Fisheries and Marine Science, Bogor Agricultural University, St. Agatis-FPIK Building, Dramaga, Bogor, West Java, Indonesia)
Nur Syafiqoh (Department of Microbiology, Faculty of Mathemeatic and Natural Sciences, Bogor Agricultural University, Dramaga, Bogor, West Java, Indonesia)
Kustiariyah Tarman (Department of Aquatic Products Technology, Faculty of Fisheries and Marine Science, Bogor Agricultural University, St. Agatis-FPIK Building, Dramaga, Bogor, West Java, Indonesia)



Article Info

Publish Date
31 Aug 2017

Abstract

Multidrug-resistant (MDR) bacteria infections become a serious problem for these several decades. To solve this issue, finding of new antibiotics candidate in an urgency. Natural pigment is known to has biological activity against pathogenic bacteria. Coastal fungi are unexplored source of natural pigment to fight MDR bacteria. This research was aimed to isolate coastal endophytic fungi from smooth ant plant (Hydophytum formicarum), to screen endophytic fungi which produce red pigment, to extract the red pigment, to determine antibacterial activity of the red pigment and to identify the coastal endophytic fungi producing the red pigment. In this study, 7 fungi were isolated as endophytic fungi from H. formicarum. There were 3 isolates which produced extracellular pigment i.e. RS 1A which produced red pigment, RS 3 produced black pigment and RS 6A produced yellow pigment.  Our study focused on red pigment which is produced by endophytic fungus strain RS 1A. The yield of red pigment was 8.8657% (w/w).  This study showed that red pigment had antibacterial activity against Escherichia coli, Acinetobacter baumannii and Proteus mirabilis strain MDR. Judging from molecular and morphological identification, the endophytic fungus strain RS 1A was identified as Aspergillus versicolor.

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Journal Info

Abbrev

biotropia

Publisher

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Veterinary

Description

BIOTROPIA, The Southeast Asian Journal of Tropical Biology, is a scientific publication of the Southeast Asian Ministers of Education Organization (SEAMEO) – Southeast Asian Regional Center for Tropical Biology (BIOTROP). It publishes articles in the broad areas of tropical ecosystems and ...