Jurnal Farmamedika (Pharmamedica Journal)
Vol 2 No 1 (2017): Jurnal Farmamedika (Pharmamedica Journal)

OPTIMASI WAKTU MASERASI PARASETAMOL DALAM JAMU PEGAL LINU YANG BEREDAR DI BOGOR BARAT

Bina Lohita Sari (Program Studi Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Pakuan)
Harry Noviardi (Sekolah Tinggi Teknologi Industri dan Farmasi Bogor)
Nur Apriani Kartini (Sekolah Tinggi Teknologi Industri dan Farmasi Bogor)



Article Info

Publish Date
12 Jun 2017

Abstract

Jamu is a traditional medicine that is consumed by people.One type of herbal medicine on the market is Jamu Pegal Linu. Indonesian Govermment’s rule that this traditional medicine may not contain any synthetic chemical substance or drug functioned isolated compound. In reality there are still found some jamu pegal linu that contain medicine compound especially paracetamol. Analyzis chemical of drugs in herbal medicine has not been accompanied by the optimum times extraction. The aim of research to optimize of the time maceration and determine the contained of paracetamol in jamu pegal linu had circulated in Bogor Barat. Sample was taken by purposive sampling. Maceration from samples were using ethanol were within varying. Analysis of thin layer chromatography was using silica gel GF254 as the stationary phase, chloroform:ethanol (9:1) as the mobile phase with short waved UV as detection method. The results showed that 7 samples contained paracetamol from 10 samples of jamu pegal linu. The optimum of the time maceration between 0-30 minutes for herbal optimum simulation, sample D, F and S with a concentration of 2,49 to 22,33 %. The optimum of the time maceration between 60-90 minutes for the sample A, E and Q with levels of 4,47 to 7,12 %. Sample H had the optimum maceration time for 120 minutes with a concentration of 18.38%. Optimization of sample maceration time is dominated by the span of time between 30-90 minutes. Therefore, it is known that the samples of jamu pegal linu spread had maceration on the optimal time period between 30-90 minutes.

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Journal Info

Abbrev

farmamedika

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Medicine & Pharmacology

Description

Jurnal Farmamedika dikelola oleh Lembag Penelitian dan Pengabdian Masyarakat, Sekolah Tinggi Teknologi Industri dan Farmasi Bogor. Frekuensi penerbitan jurnal sebanyak 2 kali dalam satu tahun pada bulan Juni dan Desember. Kategori tulisan berupa hasil penelitian dari peneliti maupun akademisi dalam ...