EKSAKTA: Journal of Sciences and Data Analysis
VOLUME 19, ISSUE 1, February 2019

Validasi Metode Bioanalisis Vankomisin HCl dalam Spiked-plasma Manusia Menggunakan KCKT-UV untuk Aplikasi PKOD

Ari Wibowo (Department of Pharmacy, Universitas Islam Indonesia)
Damas Inggil Maulidina (Department of Pharmacy, Universitas Islam Indonesia)
Wahyuni Shalatan Fitri (Department of Pharmacy, Universitas Islam Indonesia)
Vitarani Ningrum (Department of Pharmacy, Universitas Islam Indonesia)

Article Info

Publish Date
25 Feb 2019

Abstract

As the first-line antibiotic for the treatment of infections caused by methicillin-resistant Staphylococcus aureus  (MRSA), vancomycin has  a narrow therapeutic index with high pharmacokinetic   variability. Therefore, it is deemed necessary to examine its concentration in the blood as a strategy to monitor the fulfillment of therapeutic levels  in patients receiving vancomycin. This study aimed to validate vancomycin bioanalysis  in  spiked-human  plasma  for  the  applications  of  therapeutic  drug  monitoring  (TDM).

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Journal Info
EKSAKTA: Journal of Sciences and Data Analysis
Website

Abbrev

eksakta

Publisher

Universitas Islam Indonesia

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Materials Science & Nanotechnology

Description

Ekstakta is an interdisciplinary journal with the scope of mathematics and natural sciences that is published by Fakultas MIPA Universitas Islam Indonesia. All submitted papers should describe original, innovatory research, and modelling research indicating their basic idea for potential ...