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All Journal EKSAKTA: Journal of Sciences and Data Analysis
Vitarani Ningrum
Department of Pharmacy, Universitas Islam Indonesia
Chemical Engineering, Chemistry & Bioengineering Chemistry Earth & Planetary Sciences Materials Science & Nanotechnology

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Validasi Metode Bioanalisis Vankomisin HCl dalam Spiked-plasma Manusia Menggunakan KCKT-UV untuk Aplikasi PKOD Ari Wibowo; Damas Inggil Maulidina; Wahyuni Shalatan Fitri; Vitarani Ningrum
EKSAKTA: Journal of Sciences and Data Analysis VOLUME 19, ISSUE 1, February 2019
Publisher : Fakultas Matematika dan Ilmu Pengetahuan Alam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20885/eksakta.vol19.iss1.art6

Abstract

As the first-line antibiotic for the treatment of infections caused by methicillin-resistant Staphylococcus aureus  (MRSA), vancomycin has  a narrow therapeutic index with high pharmacokinetic   variability. Therefore, it is deemed necessary to examine its concentration in the blood as a strategy to monitor the fulfillment of therapeutic levels  in patients receiving vancomycin. This study aimed to validate vancomycin bioanalysis  in  spiked-human  plasma  for  the  applications  of  therapeutic  drug  monitoring  (TDM).
Co-Authors Ari Wibowo Damas Inggil Maulidina Wahyuni Shalatan Fitri