Effects of STN-DBS on Depression and Cognitive Status Dementia in Patients with Parkinson’s Disease

Vahid Ghadri (Phd Candidate Psychology, Azad University Science and Research Branch, Theran)
Omid Rezael (M.D, Associate Professor of Psychiatry, Psychosis Research Center, Psychiatry Department, University of Social Welfare and Rehabilitation Sciences, Tehran)
Muhammad Ebrahimzadeh Mousavi (M.S in Clinical Psychology, Department of Clinical Psychology, Faculty of Behavioral Science, University of Social Welfare and Rehabilitation Sciences, Tehran)
Mansour Parvaresh (M.D, Associate Professor of Neurosurgery Rasoul-e-Akram Hospital, Iran University of Medical Sciences (IUMS), Tehran)
Sadegh Ghadri (M.D. Neurosurgeon. University of Medical Science Iran, Tehran)

Budapest International Research in Exact Sciences (BirEx Journal)
Vol 1, No 1 (2019): Budapest International Research in Exact Sciences, January

Non-motor symptoms such as depression and in later phases dementia are common features of Parkinson’s disease. For the first time in Iran, the present study aims to examine the effects of deep brain stimulation of the subthalamic nucleys (STN-DBS) on cognition and mood through neuropsychological assessment of patients with Parkinson’s disease. Stimulation of the subthalamic has no negative effect on the short-term cognitive status of patients with Parkinson’s disease, and improves depression. Precise psychological evaluation helps better recognition of the effects of this kind of surgery, which may be useful in providing quality services for those who will be candidates for this surgery in the future.