Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI)
Vol 4 No 1 (2020): Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI)

Perbedaan jumlah mikronukleus mukosa gingiva dan mukosa bukal akibat radiasi radiografi panoramik

Mufida Dzuriyatin Syarifah (Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta, Indonesia, 55281)
Rini Widyaningrum (Departemen Radiologi Kedokteran Gigi, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta, Indonesia, 55281)
Rurie Ratna Shantiningsih (Departemen Radiologi Kedokteran Gigi, Fakultas Kedokteran Gigi, Universitas Gadjah Mada, Yogyakarta, Indonesia, 55281)



Article Info

Publish Date
10 May 2020

Abstract

Objectives: Panoramic radiography exposure causes DNA damage and micronucleus formation. The gingival mucosa and buccal mucosa were used to identify the number of micronucleus due to radiation exposure because they have a high prevalence of oral cancer in Southeast Asia. This research is aimed to determine the difference between micronucleus formation at the buccal mucosa and the gingival mucosa after exposed by conventional panoramic radiography in the Dentomaxillofacial Radiology Installation of Prof. Soedomo dental hospital, Universitas Gadjah Mada. Material and Methods: Samples were obtained by rolling the cervical brush against the buccal and gingival mucosa at 10 days after radiation exposure. Samples were stained using the Feulgen-Rossenbeck method and analyzed under binuclear light microscope with a 400x magnification. Results: Analysis of independent T tests showed that there was a significant difference (p<0,05) in the increasing of micronucleus formation between the buccal mucosa and the gingival mucosa. The average difference in the number of micronucleus were 5,5/1000 cells. Conclusion: There were differences in the increasing of micronucleus between the buccal mucosa and the gingival mucosa due to exposure of conventional panoramic radiography. The buccal mucosa had higher increase than the gingival mucosa.

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Journal Info

Abbrev

jrdi

Publisher

Subject

Dentistry Energy Health Professions Medicine & Pharmacology Physics

Description

JRDI is designated as a publication platform of scientific knowledge, mainly publishing research articles, case reports, literature reviews and accepting any other kind of evidence-based submissions: systematic reviews, meta-analysis, etc. JRDI receives manuscripts particularly in the area of ...