Indian Journal of Forensic Medicine & Toxicology
Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology

Hyperlipidemia that Induced in Male Rats and Role of Flavonoids Extract of Quercus infectoria in Treatment

Marwa Amer Shakir1, Iman Nozad Mahmood1 (Unknown)



Article Info

Publish Date
16 Jan 2020

Abstract

The aim of the study demonstrates flavonoids of Quercus infectoria as anti-hyperlipidemia. 20 adult male rats used and divided to four equal groups (each group consist 5 rats); rats received ad libidium, rats were given normal water containing 0.5% of hydrogen peroxide and 1% of cholesterol in the feed for 60 days for induction of hyperlipidemia. Hyperlipidemia rats treated with (50mg/kg/daily) flavonoids, fourth Hyperlipidemia rats treated with (100mg/kg/daily) flavonoids. The results show non-significant changes (P < 0.05) in levels of HMG-raductase compare with control group. in hyperlipidemia rats, levels of malonedialdehyied (MDA) show significant increase (P < 0.05) in and significant decrease (P < 0.05) in levels of glutathione (GSH) and catalase compare with control group. While, after using flavonoids extract in treatment, the results showed non-significant changes (P < 0.05) in HMG-raductase, MDA, GSH and catalase compare with control group. It was concluded that flavonoids extract of Q. infectoria extract has been a protective effect in rats with hyperlipidemia.

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