Indian Journal of Forensic Medicine & Toxicology
Vol. 14 No. 1 (2020): Indian Journal of Forensic Medicine & Toxicology

Association among Vitamin D Deficiency with some Inflammatory Marker in Iraqi Patients with Autoimmune Thyroiditis

Noor Alhuda Kh. Ibrahim1, Zaid Nsaif Abbas2, Wasnaa J. mohammad1 (Unknown)



Article Info

Publish Date
16 Jan 2020

Abstract

Background: Hashimoto thyroiditis (HT) is a common chronic autoimmune disease of the thyroid gland, characterized by painless goiter and elevated thyroid antibodies. Hypovitaminosis D (vitamin D insufficiency and deficiency) is common among patients with HT.Method: : the study include (60) subjects compared with 30 apparently healthy control group were visiting nursing home hospital in Baghdad medical city, Levels of serum thyroid-stimulating hormone (TSH), free-triiodothyronine (FT3), free thyroxine (FT4), TgAbs, and TPOAbs were determined with automated immuno chemiluminescent assay (ICMA) kits (Abbott Laboratories, IL, USA). Levels of serum 25-hydroxyvitamin D 25(OH) D) were determined using a competitive protein-binding assay (Roche Diagnostics, Mannheim, Germany). The inter-assay variation coefficient for 25(OH)D measurement was 8.5%.Results: the level of the study parameters in autoimmune thyroiditis which show significant correlation in age ,BMI, vitamin D, anti TPO antibody,IL-17, TNF-? and thyroid function (p<0.05) (p<0.01) test but calcium shoe non significant correlation between patients and control group.Conclusion: The present work shows a significant association between circulating 25(OH)D and HT, also IL-17.

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