INDONESIAN JOURNAL OF LEGAL AND FORENSIC SCIENCES
Vol 5 (2015): Indonesian Journal of Legal and Forensic Sciences

PENGARUH pH DAN LAMA PENYIMPANAN TERHADAP STABILITAS KIMIA STANDAR (+)-KATEKIN

Ni Putu Eka Leliqia (Unknown)
Yanita Ristanti Purwitadewi (Unknown)
I Made Agus Gelgel Wirasuta (Unknown)



Article Info

Publish Date
01 Feb 2015

Abstract

(+)-Catechin was a potential compound to be isolated and developed into natural antioxidant product, but it was unstable because it was easy to be oxidized and formed quinone metabolite. This became a problem in its development and isolation process. Factors that can influence the oxidation process of (+)-catechin were pH condition and storage time. Therefore, this research was conducted to know pH and storage time influence towards the (+)-catechin stability. Observation was done in two parameters which was the acid-base pH (pH 1,64-10) and the storage time for 8 days. The influence of both the parameters towards (+)-catechin standard stability was observed by the quinone metabolite formation from (+)-catechin oxidation reaction result. (+)-catechin was declared as unstable if quinone metabolite was formed by absorbance measurement in its maximum wavelength, 409nm with spectrophotometry method. The obtained result showed that (+)-catechin standard was stable in pH 1.64-6 for 8 days storage and was unstable in pH 7-10 showed by the formation of quinone metabolite for 2-8 days storage.

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Journal Info

Abbrev

ijlfs

Publisher

Subject

Chemistry Dentistry Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology

Description

AIFI berdiri sejak Februari 2010 di Jakarta didirikan oleh tokoh-tokoh Ilmuan Forensik Indonesia yang berkumpul di Jakarta dalam dua periode pertemuan. Semua ilmuan forensik yang hadir pada saat itu dinyatakan sebagai pendiri asosiasi ini. Pendiri sepakat dengan mufakat memilih Prof. Dr. Oetarjo ...