<![CDATA[The continuous resistance of pathogenic bacteria to antibiotics and failure of treatment of human diseases cause by these micrograms in addition to important of withania somniera plant in herbs medicine the present study carried out to assessment the antibacterial effect of three types of leaf extract : acetone , methanol and water in different concentrations to four multidrug resistance pathogenic isolates were selected two Gram positive and two Gram negative , the result showed that all types of isolated were inhibited by leaf extracts whereas the acetone record the highest effect were the inhibition zone (millimeter ) of growth of four bacteria isolates pseudomonas aeruginosa ,Klebsiella pneumonia , Staphylococcus aureus and Streptococcus pneumonia reach 15,14,13 15 mm respectively at 100 mg / ml concentration of acetone , the current finding indicated that leaf extracts useful as a good natural alternative drug from antibiotics in treatment of numerous infectious diseases these result from both Gram positive and Gram negative bacteria .]]>
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