Indian Journal of Forensic Medicine & Toxicology
Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology

Activity of Extract Seed Moringa Oleifera on Gene Expression of (EFB1) Gene in Candida dubliniensis Isolated from oral Candidiasis to Cancer Patients

Zahraa Khudhair Abbas Al-Khafaji1 Farqad Abdulelah Ali AL-Janahi2 , Al-karrar Kais abdul Jaleel Duai (Unknown)



Article Info

Publish Date
29 Oct 2020

Abstract

Gene expression of EFB1 gene in yeast Candida dubliniensis isolated from oral candidiasis in cancerpatients was detected using by R-time PCR for some isolates before and during the yeast infection of theepithelial cells. The results showed a high rate of gene expression of T2 ( 42.104 ± 6.533) and a significantdifference at the probability level P>0.01 compared with the treatment was c (1.034 ± 0.126 ) and the useof the Moringa oleifera extract was 25% to evaluate its effect on the gene expression (ALS1) before andduring yeast infection of epithelial cells. The results showed that the gene expression of T1 was decreasedby ( 0.129 ± 0.021) compared to (C) value (1.034 ± 0.126) .As for the T2 treatment was gene expression at a rate (42.104 ± 6.533) high Compared with T3 treatment inwhich gene expression dropped at a rate (22.143 ± 4.176 ) and with a significant difference at the level ofthe probability of P ? 0.01.

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