<![CDATA[Disinfection of root canal using root canal medicaments is considered to be an essential step for a successfulendodontic treatment. Ideal requisite of intracanal madicaments is the disinfection of the root canal andrendering it free of bacteria without causing harm to the tooth and oral tissues. Most commonly usedintracanal medicaments are calcium hydroxide, chlorhexidine and iodine potassium iodide. Sodium chlorideis not preferred as a medicament due to its property of irritating the surrounding tissues. Dentin has aninherent inhibiting effect on intracanal medicaments as it has the buffering effect which tends to neutralisethe pH of the medicaments rendering them with decreased antibacterial property. The antibacterial effect of amedicament indicates its level of action. More the antibacterial action, less the dentinal inhibition. A reviewof scientific literature was done using databases such as pubmed, google scholar, MESH and so on. The timeframe of the articles taken is between 2000 to 2020. The results are based on previous studies done on thistopic. Newer methods such as bioactive glass, photon induced acoustic streaming and gentlewave systemwere introduced to overcome this discrepancy in disinfecting the root canal. Even though the success rates ofendodontic treatments are high, it can be improved by researching and using newer and better materials forelimination of bacteria. Thus, in this review we have analysed the relation between root canal medicamentsand their inhibition by dentin.]]>
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