Indian Journal of Forensic Medicine & Toxicology
Vol. 14 No. 4 (2020): Indian Journal of Forensic Medicine & Toxicology

Role of Vitamin C in Immune Function of Human Body

V.Nancy Selvamary1 , M.P.Brundha2 , A.S.Smiline Girija3 (Unknown)



Article Info

Publish Date
29 Oct 2020

Abstract

Vitamin C is an important micronutrient for humans with pleiotropic function associated with its ability todonate electrons. It is a potent antioxidant and a cofactor for a family of biosynthetic and gene regulatoryenzymes. Vitamin C contributes to immune system defense by supporting various cellular functions ofboth the innate and adaptive immune system. Vitamin C supports epithelial barrier function againstenvironmental oxidative stress. Vitamin C accumulates in phagocytic cells like neutrophils, and mayenhance chemotaxis, phagocytosis, generation of reactive oxygen species and ultimately microbial killing.It is also needed for apoptosis and clearance of the spent neutrophils from sites of infection by macrophages.Vitamin C deficiency leads to impaired immunity and better susceptibility to infections. In turn infectionssignificantly impact on Vitamin C levels thanks to enhanced inflammation and metabolic requirements. Incontrast treatment of established infections requires a significantly higher dose of vitamin to catch up onthe increased inflammatory response and metabolic demand.one of the most reasons people take vitamin csupplements is to spice up their immunity as vitamin C is involved in many parts of the immune system.First, vitamin c helps encourage the assembly of white blood cells known as lymphocytes and phagocyteswhich helps to protect the body against various infections. Vitamin C is a strong antioxidant that can boostblood antioxidant levels and vitamin c rich foods and supplements have been linked to reduce blood uricacid levels. Many studies show vitamin c intake lower risk of several cancers and also reduced risks of eyediseases . Vitamin Cis an essential nutrient for healthy immune function. The main aim of the paper is toknow the role of Vitamin C in immune function of the human body.

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