<![CDATA[Background: The kidney is the most likely to be affected by endothelial injury in patients with preeclampsia,so assessment of renal function is essential in the evaluation of the pregnant women with preeclampsia. Aimof the study: to evaluate which test of renal function in preeclamptic patients with and without intrauterinegrowth restriction is more useful. Patients and method:150 women in third trimester with preeclampsiaover period of 14 months diagnosed based on measurement of blood pressure and presence of proteinuriadivided into two group : group A those preeclamptic women without feature of intrauterine growth restrictionby ultrasound and Doppler study and group B those with features of intrauterine growth restriction. Bloodaspirated from each woman and blood urea, serum creatinine, serum uric acid, and serum cystatin-C weremeasured using spectrophotometer. Results: From 150 women with preeclampsia 120 of them had nofeatures of intrauterine growth restriction and 30 had some features. Mean maternal age of patients includedwas 22±0.3 in group A and 24±0.7 in group B which is not differ statistically while the body mass indexshould statistically differences between the two group with P value <0.001. the blood urea, serum creatinineand serum uric acid levels found to be higher in group B but not reach statistical differences while serumcystatin C are higher in group B mean 1.23±0.45when compared to group A 1.08±0.97with p value <0.001.Conclusion:Renal function may be affected more in patients with intrauterine growth restriction and cystatinC level is more promising marker for renal function in preeeclamptic women.]]>
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