The state of equilibrium of Dosha, Dhatus, Malas is health and its disequilibrium is known as disease. Thisdisequilibrium may either be Vriddhi or Kshaya. Asthiis thefifth Dhatu among the seven Dhatus .It is theseat of vatadosha and carrying the function of dehadharana. Asthikshayais one of the condition described byAcharya Charak under 18 types Kshaya in which there is kshayaof Asthi Dhatu. According to the principle ofAshraya-ashrayee Bhava, Asthi & Vata are inversely proportional to each other regarding Vriddhi and Kshaya.Vriddhvata leads to Kshaya of Asthi Dhatu. The symptoms of Asthikshaya resemble to Osteoporosis which ismajor health problem of ageing population. It is a skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility and susceptibility tofracture. Fracture is the most common complication of Osteoporosis which increases the risk of morbidityas well as mortality. Vatais the major factor in the Samprapti of Asthikshaya, Sampraptiof Asthikshayaoccurs in two ways- Dhatukshayajanya and Srotorodhajanya. In Srotorodhajanya, the obstruction can becleared by the use of Deepana and Pachana Dravyas. Nidanparivarjana, Shodhanachikitsa including Basti,Shamana Chikitsa including use of Swayoni Dravyas, Sudha Vargiya Dravyas, Guggulukalapa are the majortreatment modalities for Asthikshaya. They help in Vatashamana and as well as improving the bone health.By following Dincharya, Rutucharya and diet regulation, this disease can be prevented. This review articlehighlights on etiopathogenesis of Asthikshaya and its measures as per Ayurvedic perspective.
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