Ameloblastomas have many microscopic and clinical variations. Typically it has three biologic variants whichinclude solid, cystic and peripheral, out of which 14% to 22% of all cases are unicystic. Rare variantslikegranular cell subtype composed exclusively of eosinophilic granular cells present inboth peripheral andinner layers of tumoral islands. This is a unique case of cystic ameloblastoma affecting a 16-year-old malewith an unusual radiographic and microscopic pattern. This rare variant will create awareness for oral andmaxillofacial pathologists for a proper pathway of diagnosis.
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