Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)
Vol. 1 No. 2 (2017): Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)

UJI AKTIVITAS ANTIBAKTERI GEL EKSTRAK DAUN PETAI (Parkia SpeciosaHassk.) TERHADAP BAKTERI STAPHYLOCOCCUSAUREUS

Nafi’ah, Rahma (Unknown)
Haryati, Etty (Unknown)
Tamara, Neneng Cahya (Unknown)



Article Info

Publish Date
08 Jan 2018

Abstract

Background: Petai leaf (Parkia Speciosa Hassk) contains flavonoids and terpenoids that are suspected of having antibacterial activity. KHM values ??were tested at 2.5% extract concentration, 5.0% and 7.5%. From the results of KHM values ??obtained then developed formulations using gel base HPMC, Karbopol and Gom Arab. Objective: To find out the value of KHM from petai leaf extract (Parkia Speciosa Hassk) and gel base which has the best and stable antibacterial activity value to storage condition. Methods: This research method using a kind of experimental research. The test results were analyzed using a statistical calculation method Analysis Of variance (ANOVA) one line and then proceed with the t-test method. Result: The results showed that parkia speciosa leaf extract contains compounds terpenoid and flavonoid, and have antibacterial activity, MIC parkia speciosa leaf extract 2,5%, all gel formulation has antibacterial activity. The carbopol base gel has the most excellent antibacterial activity. All gel formulation is stable at a temperature of 25oC, less stable at a temperature of 0oC and 40oC . Conclusion: At 2.5% concentration, petai leaf extract already has antibacterial activity against Staphylococcus aureus bacteria.

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Journal Info

Abbrev

jhhs

Publisher

Subject

Health Professions Medicine & Pharmacology Nursing Public Health

Description

Journal of Holistic and Health Sciences (JHHS) menerima naskah hasil penelitian di bidang gizi dan farmasi, khususnya di bidang gizi dan farmasi holistik. Scope JHHS yaitu: 1. Produksi Farmasi meliputi pemuatan sediaan farmasi, Skrinning fitokimia, Uji khasiat sediaan obat, 2. Pelayanan Farmasi ...