Current Research on Biosciences and Biotechnology
Vol. 2 No. 2 (2021)

The activity of bioactive compounds against several diseases by modulating autophagy

Nurinanda Prisky Qomaladewi (University Center of Excellence for Nutraceuticals, Biosciences and Biotechnology Research Center, Bandung Institute of Technology, West Java, Indonesia)
Jae Youl Cho (Integrative Biotechnology, Sungkyunkwan University, South Korea)

Article Info

Publish Date
28 Feb 2021

Abstract

Several bioactive compounds derived from Indonesia plants, such as xanthorrhizol, gingerol, and pinostrobin are the major compound in a certain plant. They have some pharmacological activities against several diseases, such as inflammation, tumor, and cancer, and modulate other mechanisms. One of them is one of programmed cell death called autophagy. The regulation involves several pathways on upstream and downstream of the autophagy mechanism and affects its activity. Each of the compound has different site of target when it comes to different case of diseases. Here we explained how the bioactive compounds regulate autophagy against several diseases.

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Journal Info
Current Research on Biosciences and Biotechnology
Website

Abbrev

crbb

Publisher

Institut Teknologi Bandung

Subject

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Materials Science & Nanotechnology Medicine & Pharmacology

Description

The Current Research on Biosciences and Biotechnology (CRBB) encourages researchers to publish works related to the use of the biosciences and biotechnology in understanding the world around us. From Health and Medicine to Advanced Materials, these state-of-the-art research offer novel insights in a ...