Nurinanda Prisky Qomaladewi
University Center of Excellence for Nutraceuticals, Biosciences and Biotechnology Research Center, Bandung Institute of Technology, West Java, Indonesia

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The activity of bioactive compounds against several diseases by modulating autophagy Nurinanda Prisky Qomaladewi; Jae Youl Cho
Current Research on Bioscences and Biotechnology Vol. 2 No. 2 (2021)
Publisher : Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/crbb.2021.2.2/WIWB7317

Abstract

Several bioactive compounds derived from Indonesia plants, such as xanthorrhizol, gingerol, and pinostrobin are the major compound in a certain plant. They have some pharmacological activities against several diseases, such as inflammation, tumor, and cancer, and modulate other mechanisms. One of them is one of programmed cell death called autophagy. The regulation involves several pathways on upstream and downstream of the autophagy mechanism and affects its activity. Each of the compound has different site of target when it comes to different case of diseases. Here we explained how the bioactive compounds regulate autophagy against several diseases.