Background : Regency of Kepulauan Yapen through Finger Blood Survey in 2006 was established as a filariasis endemic region. In 2007 started the implementation of mass treatment was held once a year for 5 years. Based on the survey of microfilaria at January 2010, the microfilaria ratewas 2.06%, where the largest number of people was in the District Windesi. Method : The study was an analytic survey with a case control approach. Population was resident in the village of Saruman and Windesi. The determination of the cases and control was done trough screening tests and found 10 cases of Wuchereria bancrofti.The ratio 1: 2, then the number of samples was 30, which was matched by age, sex and type of work. Result : The results were characteristics of filariasis patients, 30% in ≤ 20 year age group (≥ 15 years) and 21-30 years, 50% as farmers, 70% low income level (
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