Green Medical Journal
Vol 3 No 1 April (2021): Green Medical Journal

Potensi Inhibitor Protein Non-struktural 1 (NS1) Berbasis Peptida untuk Mengobstruksi Replikasi Virus Dengue (DENV): Sebuah Kajian Literatur

Asyura, Muhammad Mikail Athif Zhafir (Unknown)
Fauzi, Ahmad (Unknown)
Ayub, Fakhru Adlan (Unknown)



Article Info

Publish Date
29 Apr 2021

Abstract

Introduction: Dengue Virus (DENV) is the pathogen for human dengue fever and is responsible for 390 million infections per year. The viral genome produces about 10 viral protein products, one of them being NS1. The NS1 protein plays a key role in viral replication and stimulation of humoral immune cells, thus being the perfect candidate to create an effective antiviral drug or vaccine for dengue Methods: Dengue Virus (DENV) is the pathogen for human dengue fever and is responsible for 390 million infections per year. The viral genome produces about 10 viral protein products, one of them being NS1. The NS1 protein plays a key role in viral replication and stimulation of humoral immune cells, thus being the perfect candidate to create an effective antiviral drug or vaccine for dengue Conclusion: The review established promising results of using peptide-based intervention on NS1. Further in vivo and randomized controlled trials are advised to solidify the applicability and biosafety of the intervention

Copyrights © 2021






Journal Info

Abbrev

gmj

Publisher

Subject

Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health

Description

Green Medical Journal (GMJ) is a peer-reviewed, open-access journal that publishes original research articles, review articles, and interesting case reports. The journal focuses on promoting medical and health sciences, derived from basic sciences, clinical and community health research, both in ...