EduChemia: Jurnal Kimia dan Pendidikan
Vol 6, No 1 (2021)

Amino Acids Composition of Non-Structural Protein in SARS-CoV-2 the Cause of COVID-19 Pandemic

Suprianto Suprianto (Program Studi Pendidikan Biologi, Universitas Tadulako, Palu, 94148, Indonesia)
Ni Kadek Dewi Permatasari (Program Studi Pendidikan Biologi, Universitas Tadulako, Palu, 94148, Indonesia)
Gusti Ayu Kadek Yunita Safitri (Program Studi Pendidikan Biologi, Universitas Tadulako, Palu, 94148, Indonesia)



Article Info

Publish Date
28 Jan 2021

Abstract

The transmission of COVID-19 is one of the global problems that has caused many deaths. This pandemic was caused by SARS-CoV-2, which has several non-structural proteins (nsp1-nsp16). The non-structural proteins in SARS-CoV-2 have different amino acid compositions. The purpose of this study was to analyze the amino acid composition of SARS-CoV-2. This study used computational methods in silico analysis to analyze the amino acid composition of the target protein. The target protein sequence database was obtained from the NCBI website with the identity number NC_045512.2. Non-structural protein with the shortest amino acid length is owned by nsp7 (83 aa) with a molecular weight of 9239.34 Daltons, nsp9 (113 aa) with a molecular weight of 12377.54, and nsp1 (180 aa) with a molecular weight of 19774.35, while non-structural proteins with amino acid composition the longest is found in nsp3 (1945 aa) with a molecular weight of 217241.50 Daltons, nsp12 (932 aa) with a molecular weight of 106654.88 Daltons and nsp2 (638 aa) with a molecular weight of 70507.81 Daltons. The amino acid composition of each target protein varies in length, weight, and frequency. Information obtained from this reasearch result can be used as the basis for studying the characteristics of the non-structural protein in SARS-CoV-2, which causes the COVID-19 pandemic based on the composition of the constituent amino acids.

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Journal Info

Abbrev

EduChemia

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry Education Materials Science & Nanotechnology

Description

Focus and Scope Educhemia (Jurnal Kimia dan Pendidikan) is Periodicals published the results of research related to the development of science and technology in the field of Chemistry and Chemistry education as a form of intellectual property Chemistry: Organic chemistry, Inorganic chemistry, ...