KOVALEN: Jurnal Riset Kimia
Vol. 7 No. 1 (2021): Edisi April

Potential Combination of Kapok Leaf Extract (Ceiba pentandra G.) and Turmeric Extract (Curcuma domestica Va) as an Anticancer Compound

Muh. Natsir (Unknown)
Sanang Nur Safitri (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Halu Oleo University)
Oktovia Nurmawati (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Halu Oleo University)
Muh. Saleh Purnama R. (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Halu Oleo University)
Ruslan (Department of Chemistry, Faculty of Mathematics and Natural Sciences, Tadulako University)



Article Info

Publish Date
30 Apr 2021

Abstract

Combination of kapok leaf extract (Ceiba pertandra G.) and turmeric extract (Curcuma domestica Va.) was carried out to determine the potential of extracts in treating cancer with BSLT and murine cells P388. Cancer is a disease that is very feared because it’s difficult to cure, and even rarely causes death. The sample was extracted with methanol, the extract was mixed so that the mixture extract from the two samples was obtained. The results showed that in the BSLT test the mixed extract had a bioactivity against shrimp larvae with an LC50 value of 142.946 ppm. While in Leukemia P388 cell testing showed that the combination of mixed extracts had a cytotoxic effect on Leukemia P388 cancer cells with inhibitory concentration values of 54.34 ppm. This shows that the kapok leaf extract (Ceiba pentandra G.) and combination of turmeric extract (Curcuma domestica Va.) has potential and can be developed as an anticancer agent because it has an IC50 value that can inhibit murine P388 cell growth and LC50 value which can kill shrimp larvae Artemia salina L.

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Journal Info

Abbrev

kovalen

Publisher

Subject

Chemical Engineering, Chemistry & Bioengineering Chemistry

Description

KOVALEN: Jurnal Riset Kimia is a peer-reviewed journal of chemistry published by the Tadulako University, Indonesia. This journal concern with publishing the original research articles, review articles, and the current issues related to chemistry. Publishing frequency 3 issues per year, in April, ...